Cincinnati Children’s Hospital Medical Center

Cincinnati Children's COE Ceremony
Cincinnati Children’s Hospital Medical Center CCM Center of Excellence award ceremony

Recognized as a Center of Excellence on 4/17/2018

Public Announcement

Guest Concierge Services/Lodging Assistance

Address: 3333 Burnet Ave, Cincinnati, OH 45229 as well as numerous satellite locations in the greater Cincinnati area

Direct line for clinic appointments and referrals:  513-803-9082.  Please ask for Silia Creech.

Number of Outpatient CCM appointments in 2022:  73

Number of Inpatient CCM Patient Days in 2022:  17

Number of CCM Research Publications, 2012-2017: 8

Cincinnati Children’s Hospital Cavernous Malformation Program 

Core Faculty

Medical Director and Pediatric Cerebrovascular Neurosurgeon: Sudhakar Vadivelu, DO

Cerebrovascular Nurse Practitioner: Megan Beck, RN

Cerebrovascular Coordinator: Silia Creech

Cerebrovascular Physician’s Assistant:  Tim Burns, PA-C

Stroke Neurologist: John Michael Taylor, MD, Department of Neurology

Epileptologist: Francesco Mangano, DOHans Greiner, MDRavindra Arya, MD

Genetic Counselor: Katie Wusik, LGC, Department of Human Genetics

Stroke Hematologists: Adrienne Hammill, MD, Ph.D.Lori Luchtman-Jones, MD

Additional Faculty

Adult Neurosurgery: Mario Zuccarello, MD

Movement Disorder Neurology: Steve Wu, MD

Neuropsychologist: Anna Byars, PhD

Neuroradiologist: James Leach, MDBlaise Jones, MDMarguerite Care, MD

Stroke Rehabilitation: Nathan Evanson, MD, PhD

Cerebrovascular Researchers: Elisa Boscolo, Ph.D.Adrienne Hammill, MD, Ph.D.Lori Luchtman-Jones, MDSudhakar Vadivelu, DO

Summary of Cincinnati Children’s Research Program

The Cerebrovascular Center at Cincinnati Children’s Hospital Medical Center has active benchside and clinical research interests as it relates to cerebral cavernomas:

  • In collaboration with our translational vascular biology research program, individual laboratory research interests include exploration of developmental aspects of low flow vascular malformation and in elucidating the role for stem cell and progenitor differentiation to mature vascular cells in hopes of identifying molecular and genetic targets for future pharmacotherapeutics.
  • Candidate drugs are evaluated in the murine malformation models (venous malformation, hemangioma, and lymphatic malformations) for potential efficacy in preventing lesional growth and pre-clinical supportive evidence.
  • We have an ongoing clinical study evaluating mental health in children diagnosed with cerebral cavernomas. Our long-term goal here is to elucidate clinical management factors that affect mental health in children in comparison to other chronic medical conditions. Our immediate objective here is to understand the importance of needing to evaluate mental health metrics and further identify the best clinical tools for measurement.
  • We examine classification schema for developmental venous anomalies and the neuroimaging based architectural clues they may give us to their behavior.

Patient Education includes a dedicated webpage for cavernous malformation, use of Alliance to Cure Cavernous Malformation 20 Questions Answered Patient Booklet, annual patient conferences, and telehealth services.

Medical Education includes grand rounds, journal club, invited expert speakers, and dissemination of the Alliance to Cure Cavernous Malformation Clinical Care Consensus Guidelines.

Second Opinion Information

Cincinnati Children’s Hospital offers a second opinion program.  For patients and families who are unable to travel, there is a second opinion portal available that does not include a video visit.  For in person second opinions, a clinic visit with a full evaluation can be scheduled.  For onsite visits, medical records and imaging is reviewed by the multidisciplinary team, and the patient is seen in the clinic for a full evaluation and recommendations.

Please call Silia Creech at 513-803-9082 for additional information and to schedule an appointment.  More details can be found here:  Online Second Opinion | Cincinnati Children’s (

Last updated 07/27/23