By whatever name you know it - cavernous malformation, CCM, cavernoma, cavernous angioma - find information, opportunities, and hope here.
CCM Cure Magazine (Summer 2026)
Check out the newest edition of our magazine, CCM Cure, to learn how the Alliance is driving a cure and improving lives for all affected by cavernous malformation (CCM). Read CCM Cure Magazine (Summer 2026)
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Register for the Cavernous Malformation Registry If you or your child is affected by cavernous...
MoreA second chance for REC-994
In May of this year, Recursion transferred the REC-994 program to the Alliance. Now, we...
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What is cavernous malformation?
Cavernous malformation (CCM) is a blood vessel disorder of the brain and spinal cord. CCM can lead to strokes, seizures, and other neurological damage. Surgery is the only current treatment. CCM affects more than 3 million children and adults worldwide.
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Our Story
When we were founded in 2002, there was a void of cavernous malformation (CCM) research and information. Over the last 20 years, we have seized opportunities to bring scientists, patients, doctors, and industry partners together to advance a cure for CCM. Our work has driven research breakthroughs and improved patient care. We now have promising treatments just under five years away. We will persevere until we have a permanent cure for CCM – available, accessible, and affordable for all.
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